Council of Scientific and Industrial Research, Ministry of Science and Technology, GOI
IICT Logo CSIR-IICT
CSIR-Indian Institute of Chemical Technology
IICT Logo
Careers   Tenders   e-Pay   RTI   Webmail   हिंदी में


Skip Navigation Links


Business Development and Technology

Technology Profiles

  1. Thermal Insulation Coating for Metallic Sheets
  2. Modular High Rate Digester
  3. Enzymatic Degumming of Rice Bran Oil
  4. Tocopherols and Phytosterols
  5. Soybean and rice bran oil based lecithin products
  6. Anaerobic Gas Lift Reactor (AGR) – High Rate Biomethanation Technology for the Generation of Biogas and Bio-Manure from Poultry Litter
  7. Synthesis of Ctetryl Myristoleate (CMO) isomers for the treatment of inflammatory diseases
  8. Process for the Enrichment of Methyl Ricinoleate from Castor Oil Methyl Esters by Liquid-liquid Extraction
  9. Potentiometric Cholesterol Biosensor
  10. Estradiol derivatives with anti-cancer activity
  11. Integrin binding rgd-lipopeptides with gene transfer activities
  12. Synthesis of phase pure anatase titanium dioxide
  13. Recovery of aqueous sodium thiocyanate solvent from industrial process solution by nanofiltration technique
  14. Process for synthesis of novel cationic amphiphiles for intracellular delivery of biologically active compounds
  15. Glycerol-based Solid Acid and Base Catalysts useful for the Esterification and Transesterification Processes
  16. Biosensor device to determine potassium concentration in human blood serum
  17. Process for synthesis of glycomimicking cationic amphiphiles
  18. Irreversible temperature sensitive labels for pharmaceutical industry
  19. Process for Bleached Wax from Crude Rice Bran Wax
  20. Process for the isolation of triacontanol from rice bran wax
  21. Annona Seed Extract as Insecticide
  22. Neem Seed Extract as Insecticide
  23. Nitriminoimidazole (NIIMD)
  24. Bisphenol-Diazonaphthaquinone sulfonyl Esters - Photoactivating Compound
  25. Diazonaphthaquinone sulfonylchloride
  26. Pyriproxyfen
  27. Profenofos
  28. Process Development of Misoprostol
  29. 1,1,1,2-Tetrafluoroethane (HFC-134a)
  30. An improved process for the preparation of 2H-Heptafluoropropane
  31. 1,1,1-trifluoro trichloroethane (CFC-113a)
  32. Trifluoro acetic acid
  33. 2,2,2-Trifluoro ethanol
  34. Samadhan Kendra
  35. Pyridone derivatives
  36. Avobenzone
 
Thermal Insulation Coating for Metallic Sheets
Title of Product/ Process/ Design/ Equipment Process for the preparation and testing of Thermal insulation coating for metallic sheets
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Developed three variants of coatings ( Solvent based/water based /High Solids Coatings):

One Indian patent filed jointly with Tata Steel Ltd.: “A Composition of Eco-friendly thermal insulation color coating for application on the inner surface of galvanized steel sheets for Roofing application (India Patent Application1418/KOL/2011,Filed June 2011) Other variants patent filing under process.

Knowledge base available for variation of compositions suitable for other substrates & customized solutions as per requirements of end users.
Application/Uses Piping & Processing equipments, Roofing & Cladding (coat and foam sandwich), Ware Housing & other similar applications
Salient Technical Features including Competing Features Temperature difference (δT, between outer and inner surface of substrate Steel) ~ 8-150C ( based on coating thickness , thickness range 0.5 to 1.0 mm and above, nanotech lower thickness)

Adhesion: Very good on primed/treated galvanized steel, and carbon Steel).

Thermal Stability: -300C to 2000C without appreciable weight loss (TGA).

Thermal Stability: -300C to 2000C without appreciable weight loss (TGA).

Flexibility,Hradness & Impact: Very Good ( Falling weight, can be tuned as per specifications)

Drilling Characteristics: Good without flakes

Colour: Off white, Grey, Dark Grey, Light blue to dark blue

Finish: Matt to glossy
Level/Scale of Development Laboratory scale, 10 Litres (1-2 Litres per batch)
Environmental Considerations Clean and/or within limit

High Solids & water based formulations for very less and solvent based compositions for moderate impact on environment.
Status of Commercialization Yet to be commercialized
Major Raw Materials to be Utilized Synthetic and Renewable Resources based Resins, Epoxy, Acrylic , Amines, Diisocyantes and their adducts, Microporous/platelike/microsphere functional filler composition, Nano/Micro Clays, Organic and Inorganic Pigments (based on color type), Additives, Solvents (based on requirement), surface treatment/priming compositions for surface preparation
Major Plant Equipment and Machinery Required Conventional paint processing equipments ( Ball/Rotatory Mills, Mixer/Blender, High Speed Disperser etc)

Paint Application: Spray, Airless Spray, Brush/Roll etc based on requirements.
Techno-Economics Comparable cost based on the type of application, finish and thickness of the coating.
Technology Package Composition of coatings based on application requirements and specifications.

Resins and adduct process technologies for backward integration

Foam process technology for sandwich type insulation.
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) Thermal Insulator Coating

...top


 
Modular High Rate Digester
Title of Product/ Process/ Design/ Equipment Modular high rate digester for safe disposal of garbage
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Patent documents submitted

Application/Uses
  • Safe disposal of garbage
  • Biogas production from any organic solid waste

Salient Technical Features including Competing Features
  • High treatment efficiency in terms of percentage solid reduction.
  • Based on high rate biomethanation technology with world class standard
  • Designed for apartments, residential colonies, hotels and canteens
  • Can be scaled-up for medium scale application in food industries, slaughter houses, tanneries and market yards
  • Fully automatic for operational convenience.
  • Feeding without size reduction & pre-processing
  • Field tested and free from operational problems
  • Field tested and free from operational problems
  • Modular design, portable, less space requirement & aesthetic looks
  • Fully sealed, completely safe & environment friendly
  • No water consumption & no secondary solids generation
  • Affordable cost
Level/Scale of Development Capacity ranges from 50 kg/day to 1 ton/day.
Environmental Considerations Environment friendly
Status of Commercialization License given to M/s Enbiopac, Kochi, Kerala. (MSME registered)
Major Raw Materials to be Utilized Source sorted garbage or any biodegradable organic solid waste
Major Plant Equipment and Machinery Required Custom designed digester made of mild steel with internal fittings, epoxy coating for contact parts, air compressor, motorized butterfly valve, process control system, & biogas holder
Techno-Economics Current practice of garbage disposal in urban areas:
In urban area each family spends Rs.50/month to dispose 25 to 30 kg of garbage. This amounts to Rs.2/kg of garbage.
In addition to this amount urban local body spends nearly Rs.600 to Rs.1000/ton for transporting and dumping the garbage in dumping yards. Therefore current expenditure for an improper garbage disposal system is Rs.3.00/kg of garbage.

Garbage disposal using digester:
Cost of digester = Rs.3.00 lakhs
Interest @ 10% = Rs.30,000/-
Depreciation @ 10% = Rs.30,000/-

Note: Digester generates 1 cu.m of biogas daily and it is equivalent to 0.3 kg of LPG. Considering cost of LPG as Rs.50/kg, revenue from biogas amounts to Rs.5475/year.

Total operating cost = (Rs.60,000 – Rs.5,475 = Rs. 54,525/-)

Digester capacity = 18.25 tons/year
Garbage disposal cost = Rs. 3.00/kg

Conclusion:
Cost for safe disposal of garbage using digester and cost towards present practice of unsafe dumping of garbage are same.
Technology Package Free of license fee for MSME as CSIR@800 initiative.

Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) Modular high rate digester installed in an apartment complex
Thermal Insulator Coating

...top


 
Enzymatic Degumming of Rice Bran Oil
Title of Product/ Process/ Design/ Equipment Modular high rate digester for safe disposal of garbage
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details
  • Indian Patent No.229300 (2006)
  • US Patent No. 7494676 (2009)
  • Vietnam Patent No. 1-0008605 (2010)
  • China Patent No. CN100347278 C (2007)
  • Japan Patent Application No. 2004-510360 dt. 25/11/2004
  • Indonesia Patent Application No. WO0200402321 dt. 21/10/2004
Application/Uses Pretreatment of Rice bran oil for making it amenable for physical refining by reducing phosphorus levels to 0 to 5 ppm after enzymatic degumming, bleaching and dewaxing
Salient Technical Features including Competing Features
  • Less Water: About 40-50% less water compared to other degumming methods
  • Less Liquid Effluent compared to other degumming methods
  • More Oil Recovery: 0.6 to 1.5% in case of physical refinery 2 to 3 folds more recovery in case of chemical refinery
  • More Fatty Acid: 0.3 to 0.6% additional fatty acid recovery
  • Better Quality Oil: Established New Processing Capacity of 2 lakh tons worth Rs. 800 Crores
  • Value Addition to By-Products:
    • High value lyso lecithin
    • Better quality wax
Level/Scale of Development 50 tonnes per day
Environmental Considerations Environmentally much more benign compared to the existing commercial processes as this process requires less water and release less liquid effluent
Status of Commercialization Commercialized. Demonstrated to 19 industries and 8 project engineering companies
Major Raw Materials to be Utilized Crude rice bran oil, Phospholipase A1
Major Plant Equipment and Machinery Required Common equipments and machineries used in the vegetable oil refining industries and a high-shear mixer
Techno-Economics Technically and economically feasible and being practiced by several Indian Rice Bran Oil Refineries
Technology Package Available
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) Thermal Insulator Coating

...top


 
Tocopherols and Phytosterols
Title of Product/ Process/ Design/ Equipment Tocopherols and Phytosterols
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details No Patent
Application/Uses Tocopherols are natural antioxidants.
α- and -tocopherols exhibit strong vitamin E and antioxidant activities respectively. Phytosterols exhibit several pharmaceutical and nutraceuticals applications.
Salient Technical Features including Competing Features The process involves
  • Esterification and transesterification to convert fatty acids and triglyceride present in Deodorizer Distillate (DOD) of soybean / sunflower oils to fatty acid methyl esters
  • Separation of phytosterols
  • Enrichment of Tocopherols using short-path distillation
Level/Scale of Development 3 to 4 Kg Soybean Oil DOD/batch
Environmental Considerations The process does not release any effluents
Status of Commercialization Transferred the Technology to two Indian Industries
Major Raw Materials to be Utilized Deodorizer distillate of soybean oil and sunflower oil (with minimum 5% of tocopherols and phytosterols each), methanol and sulfuric acid.
Major Plant Equipment and Machinery Required STR Reactor, Crystallizer and Short-path distillation unit.
Techno-Economics Technically and economically feasible and being practiced by two Indian Industries
Technology Package Available
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Soybean and rice bran oil-based lecithin products
Title of Product/ Process/ Design/ Equipment Soybean and rice bran oil-based lecithin products
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details
  • US Patent No. 6,638,544 (2003)
  • Indian Patent No.199806 (2006)
  • US Patent No. 6,403,344 (2002)
  • Indian Patent No. 227530 (2009)
  • Indian Patent Applied - 0031NF 2014 (2013)
Application/Uses Emulsifier, anti-spattering agent in margarine, confections and snack foods; wetting and dispersing agent in instant foods such as cocoa powder, drinks, coffee whiteners; browning agent and phosphate dispersant in meat and poultry processing and several other applications
Salient Technical Features including Competing Features
  • Food Grade Lecithin: Crude soybean and rice bran gums are bleached with different bleaching agents in presence of a peroxide scavenger to obtain food grade lecithin with lower peroxide value
  • Hydroxylated Lecithin: Lecithin is hydroxylated employing hydroxylating agents under microwave assisted conditions without exposing the lecithin for longer reaction times for hydroxylation
  • Acetylated Lecithin: Phosphatidylethanolamine present in lecithin is selectively acetylated employing enzymatic process
Level/Scale of Development 1 kg crude gums/batch
Environmental Considerations Environmentally safe processes
Status of Commercialization
  • Honey-like Lecithin was transferred to two Indian industries
  • Acetylated and hydroxylated lecithins have not yet been transferred to industry

Major Raw Materials to be Utilized Crude soybean lecithin, Crude rice bran lecithin, Bleaching agents, Acetylating agent, Hydroxylating agent
Major Plant Equipment and Machinery Required Stirred Tank Reactors, Vacuum Systems
Techno-Economics Technical and economical feasibility
Technology Package Available
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Anaerobic Gas Lift Reactor (AGR) – High Rate Biomethanation Technology for the Generation of Biogas and Bio-Manure from Poultry Litter
Title of Product/ Process/ Design/ Equipment Anaerobic Gas Lift Reactor (AGR) – High Rate Biomethanation Technology for the Generation of Biogas and Bio-Manure from Poultry Litter
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Applied for patent in India and PCT countries
Application Number: PT-609/0207NF2012
Application/Uses Biogas and Bio-manure generation from Poultry Litter
Salient Technical Features including Competing Features “Anaerobic Gas Lift Reactor (AGR).” was specially designed for treating poultry litter generating from Indian poultry farms having grit, sand and low C/N ratio. CSIR- IICT has designed high rate biomethanation digester, which is working successfully for poultry litter. This technology is superior in terms of biogas and bio-manure production. The technology incorporates novel grit removal system and ammonia inhibition mechanism. Installation of biogas power plants based on “AGR” would ensure a cleaner environment and provide sustainable financial dividends to farm owners by offsetting their power requirements. Safe & timely waste disposal through the AGR, coupled with the biogas energy generation, will improve the profitability of the poultry industry.
Level/Scale of Development Commercial plant working
Environmental Considerations Un treated poultry litter is mainly utilized for growing crops which may result in air, land and water pollution apart from spreading pathogenic organisms like salmonella, E.coli Un treated poultry litter is also being used in livestock feeds to lower the feed cost (especially for fish production) but may be discouraged due to potential source of pathogenic microorganisms such as salmonella. The technology is meant for scientific treatment and disposal of poultry litter through the generation of renewable energy in the form of biogas and bio-manure. It is a environmentally benign method for the reduction of GHG’s also.
Status of Commercialization Technology Licensed to M/s Ahuja Engineers (AES), Hyderabad. One ton per day plant working at Pedda Shivanoor, Chegunta Mandal near Hyderabad, India
Major Raw Materials to be Utilized Poultry Litter
Major Plant Equipment and Machinery Required Feed Preparation Tank (FPT), Hydrolysis Tank (HT), Settling Tank (ST), Anaerobic Gas Lift Reactor (AGR), Gravity Filter (GF), Balloon for biogas storage, Biogas Engine
Techno-Economics AGR Technology is economically viable solution with in the farm. The capital cost could be recovered with tangible and intangible benefits such as
  • Replacement of conventional electricity board power with renewable power generated from biogas
  • Bio-manure is a salable by product.
  • Hygiene in the poultry farm could be improved thereby sanitation could be avoided.
  • Helath of the bird will improve and egg production could be increased.
  • Mortality of the birds could be reduced.

Technology Package CSIR-IICT in association with M/s AES, Hyderabad could offer turnkey solution to the poultry farm right from conceptual stage to commissioning.
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Synthesis of Ctetryl Myristoleate (CMO) Isomers for the Treatment of Inflammatory diseases
Title of Product/ Process/ Design/ Equipment Synthesis of Cetyl Myristoleate (CMO) Isomers for the Treatment of Osteoarthritis and Other Joint Inflammatory Diseases
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details
  • US 8,816,109 (26-08-2014)
  • EP2379175 (Europe, Germany & France, 17-07-2013)
  • China Patent No. CN102348482 B (May 14, 2014)
  • Indian Patent Application No. 45/DEL/2009 dt. 12-01-2009
Application/Uses Cetyl myristoleate (CMO) is the common name for hexadecyl cis-9- myristoleate. CMO is well known for its anti-arthritis properties. The main component of CMO is cis-9 myristoleic acid, and is being isolated from selective natural sources along with other fatty acids. CMO is being sold in the market for the treatment of different forms of arthritis, osteoarthritis, as well as many other forms of diseases.
Salient Technical Features including Competing Features The process involves
  • Preparation of Myristoleic acid from oleic/undecenoic acid
  • Transesterification of Myristoleic acid with cetyl alcohol to obtain cetyl myristoleate isomers
Level/Scale of Development Lab Scale Technology (10 g/batch)
Environmental Considerations No environmental issues involved in the process
Status of Commercialization Not yet commercialized
Major Raw Materials to be Utilized Oleic acid / Undecenoic Acid, Cetyl Alcohol
Major Plant Equipment and Machinery Required Routine equipment required for any organic synthesis
Techno-Economics Technically and economically feasible
Technology Package Available for lab scale process
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Process for the Enrichment of Methyl Ricinoleate from Castor Oil Methyl Esters by Liquid-liquid Extraction
Title of Product/ Process/ Design/ Equipment Process for the Enrichment of Methyl Ricinoleate from Castor Oil Methyl Esters by Liquid-liquid Extraction
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details
  • US Patent No. US8383847 B2 (26/2/2013)
  • Europe Patent No. 2254978 (2011)
  • Britain Patent No. 2254978 (2011)
  • France Patent No. 2254978 (2011)
  • Germany Patent No. 2254978 (2011)
  • Indian Patent Application No. 520/DEL/08 dt. 05-03-2008
Application/Uses The enriched methyl ricinoleate will be useful for the preparation of castor oil derivatives without interference of non-hydroxy fatty acids.
Salient Technical Features including Competing Features A novel process was developed for the enrichment of methyl ricinoleate upto 98% purity from castor oil methyl esters by liquid-liquid extraction in a ternary system of castor oil methyl esters, refined vegetable oil or light paraffin and aqueous polar solvent.
Level/Scale of Development 3 kg castor oil fatty acid methyl ester / batch
Environmental Considerations Environmentally safe as the materials used in the process are recycled and reused
Status of Commercialization Not yet commercialized
Major Raw Materials to be Utilized Castor oil Methyl Esters, Polar solvent, Liquid Paraffin, Refined Vegetable Oil
Major Plant Equipment and Machinery Required Jacketed reactor, high efficiency distillation column, centrifugation equipment, adsorption column, vacuum rotary drier etc
Techno-Economics Technically and economically feasible
Technology Package Available
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Potentiometric Cholesterol Biosensor
Title of Product/ Process/ Design/ Equipment Potentiometric cholesterol biosensor for the quantitative estimation of total cholesterol in human blood serum
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details PatentAbroad
DE, GB, NL 087102869 2130045, US 121528758 No. 8357275
Application/Uses Detection of Cholesterol in blood serum
Salient Technical Features including Competing Features The sensor consists of an ISFET coated with molecular Imprint (MIP) of Cholesterol and a reference (Silver) electrode. It detects the potential difference in serum and converts the same to cholesterol levels.
Level/Scale of Development Lab Scale
Environmental Considerations NA
Status of Commercialization Negotiations are going on
Major Raw Materials to be Utilized Silicon Chip (ISFET), Silver electrode, Glass for packaging
Major Plant Equipment and Machinery Required Required machinery for making ISFET and packaging is available at CEERI, Pilani
Techno-Economics Costs less than Rs. 5000/-
Technology Package
  1. Method of preparation of MIP
  2. Coating of the ISFET with MIP
  3. Packaging

Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) ISFET


...top


 
Estradiol Derivatives with Anti-Cancer Activity
Title of Product/ Process/ Design/ Equipment Novel cationic 17-Estradiol-substituted-estradiol derivatives with anti-cancer activity
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Patented in India, USA, France etc.
Application/Uses Estradiol derivatives useful as anti-cancer agents against gynecological and breast cancers
Salient Technical Features including Competing Features
  1. These Estrogen-structure based molecules have the ability to kill cancer cells of all stages of breast cancer. Other existing estrogen-based or estrogenic anticancer molecule acts against estrogen receptor (ER)-expressing breast cancer cells only. So, this molecule is ‘fit-for-all’ breast cancer phenotypes.
  2. These molecules have anticancer effect against other ER-expressing cancer cells, such as ovarian carcinoma, melanoma, pancreatic cancer
  3. It is orally administrable (whereas estrogenic, anti-breast cancer drug FaslodexTM is intramuscularly injectable only). Hence, it holds the promise to become the first oral breast cancer drug developed from India
Level/Scale of Development Tested preclinically in triple negative breast tumor animal model (the most aggressive breast cancer model)
Environmental Considerations There is no major environmental concerns during product development.
Status of Commercialization Nil
Major Raw Materials to be Utilized The starting material for synthesis is estrone (a natural hormone), which is commercially available.
Major Plant Equipment and Machinery Required No major equipments required for synthesis
Techno-Economics Commercially viable, as the synthesis involves industrially inexpensive chemicals;
Technology Package Molecule is ready as a package
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Integrin binding rgd-lipopeptides with gene transfer activities
Title of Product/ Process/ Design/ Equipment Integrin binding rgd-lipopeptides with gene transfer activities
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Japan Patent No. 5078987 (Granted on 07/09/2012);
EP2004239 Granted on 03/02/2010;
US Patent Application No. 12/295107 filed on 02/06/2010
Indian Patent Application No. 0924DEL2006 filed on 31/03/2006;
PCT Patent Application No. PCT/IB07/00826 filed on March 30, 2006);
Application/Uses For delivering potent cytotoxic drugs/genes selectively to tumor vasculature in antiangiogenic cancer therapy
Salient Technical Features including Competing Features The process of the present invention can be exploited for preparing cationic lipopeptides based gene transfer reagents containing integrin-binding RGD head-groups.

The inventions of RGD-lipopeptides are useful for delivering polyanions, polypeptides or nucleopolymers into cells via 5β1 integrin receptors.

The cationic RGD-lipopeptides disclosed in this patent can be used to deliver an expression vector into a cell for manufacturing or therapeutic use. The expression vectors can be used in gene therapy protocols to deliver a therapeutically useful protein to a cell or for delivering nucleic acids encoding therapeutically useful protein molecules.

The invention RGD-lipopeptides can be formulated with anionic, zwitterionic and lipophilic therapeutic agents including anticancer agents such as doxorubicin, a lipophilic compound, to obtain complexes comprising the invention RGD-lipopeptides and a therapeutic agent(s).

In particular, the presently disclosed RGD-lipopeptides hold potential for future exploitation in delivering anti-cancer genes/drugs to tumor vasculature, the anti-angiogenic therapeutic modality to combat cancer.
Level/Scale of Development Bench scale
Environmental Considerations Non-hazardous
Status of Commercialization Not commercialized yet
Major Raw Materials to be Utilized Chemicals
Major Plant Equipment and Machinery Required Organic Chemistry laboratory and animal cell culture facility
Techno-Economics viable
Technology Package Synthetic process for preparing RGD-lipopeptides and process for delivering drugs/genes to tumor vasculature for use in anti-angiogenic cancer therapy
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) NA

...top


 
Synthesis of phase pure anatase titanium dioxide
Title of Product/ Process/ Design/ Equipment Synthesis of phase pure anatase titanium dioxide
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Title: “Simultaneous preparation of nanocrystalline anatase titanium dioxide powder and hydrazine monohydrochloride, comprises adding hydrazine monohydrate solution drop wise to acidic aqueous solution of titanium tetra chloride.”
Inventors: S. V. Manorama, K. Madhusudan Reddy, Pratyay Basak, C. K. Nisha, C. V. Gopal Reddy.
Status: Granted
Patent Number(s): US2005106095-A1; US7510694-B2; WO2005051847-A1; AU2003280080-A1; EP1685068-A1; EP1685068-B1; DE60326778-E.
Application/Uses Smart/Functional Coatings, Superior (Photo)Catalysts, Gen-III Solar Cells, High-Capacity Anodes
Salient Technical Features including Competing Features Anatase titanium finds application as a photocatalyst for removing environmental pollutants, as a pigment material, as an additive for plastic product or for optical multicoating reagent. The performance of titanium dioxide in various applications depends on its crystalline phase state, dimensions and morphology. In the present methodology the synthesis of phase pure anatase titanium dioxide is by a process at ambient conditions of temperature and pressure. The methodology is simple, green (100% atom conservation) process and environment friendly, yields the product of high purity, appreciably narrow particle size-distribution ease of up-scaling with the added advantage of a commercially viable byproduct.
Level/Scale of Development Capability of 100gm scale and can be upscaled if necessary
Environmental Considerations Environmentally friendly process
Status of Commercialization Ready
Major Raw Materials to be Utilized TiCl4, Hydrazine hydrate and water
Major Plant Equipment and Machinery Required Simple Chemistry glassware appropriate for the quantity required.
Techno-Economics  
Technology Package  
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Recovery of aqueous sodium thiocyanate solvent from industrial process solution by nanofiltration technique
Title of Product/ Process/ Design/ Equipment Recovery of aqueous sodium thiocyanate solvent from industrial process solution by nanofiltration technique
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details
  • US Patent 7314606, 1st Jan, 2008.
  • Morocco: MA Pat. No. 28551, 3rd April, 2007.
  • Indonesia: ID 0021889, 4th Sept, 2008.
  • Turkey TR200606229B 21st March, 2007.
Application/Uses
  • Aqueous sodium thiocyanate is used as a solvent for spinning of acrylic fiber which is an important component of polyester.
  • Nanofiltration process recovers about 95-99% of sodium thiocyanate in the permeate with <0.2 % thiocyanate in final reject sent for disposal as per environmental protocols.
  • Quality of fiber spun from recovered and blended sodium thiocyanate meets fiber specifications.
Salient Technical Features including Competing Features
  • A membrane-based nanofiltration process has been developed for separating sodium thiocyanate (NaSCN) from industrial solution containing impurities such as color, β-sulfopropionic acid, β-sulfopropionitrile, sodium sulfate and salts of iron and calcium. Removal of impurities such as sodium sulphate, Ca, Fe from aqueous sodium thiocyanate solution is done in a single step.
  • Nanofiltration process requires only 50% of the cost incurred by conventional adsorption in a Gel Filtration Column.
Level/Scale of Development
  • The technology has been developed on a pilot scale involving five stages with intermittent dilution for processing 100 L of feed solution containing 10-12% sodium thiocyanate and 2.5-5% impurities.
  • Commercial Nanofiltration system of 4000 L/day capacity for recovery of sodium thiocyanate was commissioned at CFCL, Haldia, West Bengal in January 2005-06.
Environmental Considerations Reject contains < 0.2% sodium thiocyanate. This reject can be sent to a multiple effect evaporator.
Status of Commercialization The commercial plant at Haldia was operated for a period of 2 years. IICT is presently not in touch with the client.
Major Raw Materials to be Utilized Industrial process solution (effluent) containing sodium thiocyanate with impurities.
Major Plant Equipment and Machinery Required Prefilter assembly, Nanofiltration membranes, Pressure vessels, Piping, instrumentation and skid, Static mixer, High pressure pump, Storage tanks for feed, permeate and reject.
Techno-Economics
  • Operation and maintenance costs of NF system was found to be 4.3 lakh per annum (Rs 73/m3 of permeate treated), which includes module and cartridge replacement cost, power cost, chemical consumption and cleaning in place (CIP) chemicals cost.
  • The capital cost of plant was earlier Rs 15 lakhs excluding cost of storage tanks.
Technology Package Process design, Process flow diagram with equipment design, Material balance, Membrane Specs, Economic estimation, Simulation program in MS Excel and Tripartite agreement with supplier.
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) Nanofiltration
Fig.1. Commercial Nanofiltration system commissioned at CFCL, Haldia, West Bengal.
Nanofiltration
Fig. 2. Photograph of Feed and Permeate Samples

...top


 
Process for synthesis of novel cationic amphiphiles for intracellular delivery of biologically active compounds
Title of Product/ Process/ Design/ Equipment Process for synthesis of novel cationic amphiphiles containing N-Hydroxyalkyl group for intracellular delivery of biologically active molecules
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian Patent 189751 (2003)
US Patent 6,541,649 (2003).
Application/Uses For delivering genes into cultured animal cells
Salient Technical Features including Competing Features The procedures for making these novel cationic amphiphiles being simple, the prices of this new transfection reagent should be remarkably lower than that of LIPOFECTAMINE™ and LIPOFECTIN™
The transfection efficiency of the novel cationic amphiphiles are much better than that of LIPOFECTIN™ and comparable to or better than the transfection efficiencies of LIPOFECTAMINE.™
The cationic amphiphiles disclosed in the present invention have been tested positive for transfecting COS 1, Hela, Vero, CV 1 and NIH3T3 cells and the primary cell line, Rat Skin Fibroblasts.
Level/Scale of Development Bench scale
Environmental Considerations Non-hazardous
Status of Commercialization Not commercialized yet
Major Raw Materials to be Utilized Chemicals
Major Plant Equipment and Machinery Required Organic Chemistry laboratory and animal cell culture facility
Techno-Economics viable
Technology Package Synthetic process for preparing the cationic amphiphiles and process for delivering drugs/genes into cultured animal cells
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) NA

...top


 
Glycerol-based Solid Acid and Base Catalysts useful for the Esterification and Transesterification Processes
Title of Product/ Process/ Design/ Equipment Glycerol-based Solid Acid and Base Catalysts useful for the Esterification and Transesterification Processes
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details
  • US08445400 (21-05-2013)
  • AU2007357284 (26-07-2012)
  • Indonesia, IDP0032300 (13-11-2012)
  • Indian Patent Application No. 1624/DEL/07 dt. 01-08-2007
  • German Patent Application No. DE112007003607 dt. 26/10/2007
  • Indian Patent Application No. 2291DEL2011 dt. 08-12-2011
Application/Uses The glycerol-based carbon catalyst economically strengthens the biodiesel industry with new application to glycerol. The catalyst reduces the effluent load by avoiding sulfuric acid during esterification of free fatty acids present in indigenous non-edible oils for the preparation of biodiesel. The catalyst is very stable and can be recycled several times. In addition, the catalyst has been successfully employed as an efficient recyclable heterogeneous catalyst in a wide variety of synthetic methodologies, showing its versatility as a green catalyst and also a potential replacement to sulphuric acid. These catalyst based reactions may lead to cleaner industrial processes in several areas like oleochemicals, pharmaceuticals, nutraceuticals, lubricants, agrochemicals etc., by reducing liquid effluents. The catalyst was further modified as base catalyst for transesterification of oils to biodiesel.
Salient Technical Features including Competing Features The process involves Simultaneous carbonization and sulfonation of glycerol with sulfuric acid
Level/Scale of Development 100 g Glycerol/batch
Environmental Considerations Residual sulphuric acid has to be removed from the product during the preparation of catalyst. However, the catalyst is a good replacement for sulphuric acid for variety of reactions, which leads to cleaner industrial processes. The base catalyst is a good replacement for alkali or alkoxides for transesterification process.
Status of Commercialization Lab scale process is ready for commercial exploitation
Major Raw Materials to be Utilized Glycerol, Sulfuric acid, Alkali
Major Plant Equipment and Machinery Required Acid resistant STR Reactor
Techno-Economics Technically and economically feasible
Technology Package Available for lab scale process
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Biosensor device to determine potassium concentration in human blood serum
Title of Product/ Process/ Design/ Equipment Biosensor device to determine potassium concentration in human blood serum.
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Patent
Abroad
US WO2007113854-B1 JP2009-502337 No. 5032560
Application/Uses Detection of Potassium in blood serum
Salient Technical Features including Competing Features The sensor consists of an ISFET coated with Crown ether and a reference (Silver) electrode. It detects the potential difference in serum and converts the same to Potassium levels.
Level/Scale of Development Lab Scale
Environmental Considerations NA
Status of Commercialization -
Major Raw Materials to be Utilized Silicon Chip (ISFET), Silver electrode, Glass for packaging
Major Plant Equipment and Machinery Required Required machinery for making ISFET and packaging is available at CEERI, Pilani
Techno-Economics Costs less than Rs. 5000/-
Technology Package
  1. Coating of the ISFET with crown ether
  2. Packaging
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) ISFET

...top


 
Process for synthesis of glycomimicking cationic amphiphiles
Title of Product/ Process/ Design/ Equipment Process for synthesis of glycomimicking cationic amphiphiles.
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian Patent Application No. 359/DEL/2006; Filed on 07-02-2006;
International Patent Application No. PCT/IB 2007/000281, filed on 07.02.2007, Publication No. WO/2008/001166, Publication date: 03.01.2008.;
US Patent No. 8278483 (Granted on 02/10/2012)
Application/Uses The process of the present invention can be exploited for preparing cationic transfection lipids with polar shikimic acid head groups. The invention lipids are useful for delivering polyanions, polypeptides or nucleopolymers into cells.
Salient Technical Features including Competing Features The expression vectors can be used in gene therapy protocols to deliver nucleic acids encoding therapeutically useful protein molecules that can generate an immune response in a host for vaccine or other immunomodulatory purposes.
Level/Scale of Development Bench scale
Environmental Considerations Non-hazardous
Status of Commercialization Not commercialized yet
Major Raw Materials to be Utilized Inexpensive Chemicals
Major Plant Equipment and Machinery Required Organic Chemistry laboratory and animal cell culture facility
Techno-Economics viable
Technology Package Synthetic process for preparing cationic amphiphiles with glycomimicking head-groups and process for delivering drugs/genes into cultured animal cells.
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) NA

...top


 
Irreversible temperature sensitive labels for pharmaceutical industry
Title of Product/ Process/ Design/ Equipment Irreversible temperature sensitive labels for Pharmaceutical industry
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details NA
Application/Uses Useful for pharmaceutical companies who manufacture the drugs to be stored in cold as indicator labels on their products. The manufacturers and the retailers would be benefited with fail safe proofing indicators that change colour. The consumers are benefited as they help them in ensuring the potency of the contents.
Salient Technical Features including Competing Features The presence of a temperature sensitive indicator on the containers of such drugs would lead to their efficient administration. The product is an irreversible temperature sensitive indicator label for the pharmaceutical industry. They are available in different colours and over a range of temperatures i.e., from 4ºc to 60ºc.
Level/Scale of Development The technology for the label that changes color irreversibly from colorless to blue or red at 4, 10, 18, 25 and 40ºC has been developed. The process know-how for colour developers, colour formers, emulsions, microencapsulation and formulations of the coatings needed to make the labels and the preparation of labels could be demonstrated at IICT for 100 g.
Environmental Considerations The labels are non-toxic and therefore are pollution averted
Status of Commercialization Ready for transfer.
Major Raw Materials to be Utilized Monomers, dye precursors, polymers & oxidizing agents
Major Plant Equipment and Machinery Required Emulsifiers, Incubator, Grinding ball mills, Reaction kettles and Label making machine
Techno-Economics Depends on the scale of production
Technology Package Yes
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) _

...top


 
Process for Bleached Wax from Crude Rice Bran Wax
Title of Product/ Process/ Design/ Equipment Process for Bleached Wax from Crude Rice Bran Wax
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian Patent No. 228674 (2009).
Japan Patent No. 4125532 (2008).
Application/Uses Rice bran wax is being used in several formulations used in paper coating, thermal transfer recording materials, surface coatings (pigment dispersant and thermal transfer ink composition preparations), toner compositions for electrostatographic image formation process, PTTE coated silicone rubber rolls, candles, water proofing, polish (floor, furniture and shoe), binder for manufacture of fuel briquettes from industrial and agricultural wastes, cosmetics (cold creams or fragrance sticks, hair conditioners, lipsticks etc.), carbon paper, printing inks, adhesives, lubricant for PVC or ABS compositions, food emulsions, egg, fruit and vegetable coatings, pharmaceuticals, plasticizing material in chewing gum etc. Rice bran wax may also be used as a substitute for the imported wax like carnauba.
Salient Technical Features including Competing Features In the first step the crude wax is upgraded by removing the oil and resinous matter selectively using an organic solvent. The upgraded wax is further bleached chemically to obtain odorless light yellow wax with the following specifications: M.P: 78-80C, AV, 0-5 (depending on AV of crude Wax); SV, 75-90; IV: 8-15. The color of the bleached wax depends on the quality of the crude rice bran wax.
Level/Scale of Development 2 kg Crude wax / batch
Environmental Considerations The process does not release any effluents
Status of Commercialization Transferred to four industries
Major Raw Materials to be Utilized Crude rice bran wax, organic solvent, bleaching agent
Major Plant Equipment and Machinery Required Jacketed Reactor, Solvent Distillation System,
Techno-Economics Technically and economically, it is a feasible process
Technology Package Available
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in

...top


 
Process for the isolation of triacontanol from rice bran wax
Title of Product/ Process/ Design/ Equipment Process for the isolation of triacontanol from rice bran wax
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian Patent No. 184307 (2001)
Application/Uses The fatty alcohol fraction produced from rice bran wax, which is usually called as triacontanol is useful for stimulating growth in a wide variety of plants, including agricultural crops such as corn, soybean, wheat, rice and tomatoes. Formulations are prepared by dissolving the triacontanol in organic solvents and then adding the solution to water with an emulsifying agent.
Salient Technical Features including Competing Features The process involves aqueous saponification of defatted rice bran wax followed by extraction of fatty alcohol mixture from the saponified mass using an appropriate organic solvent. The fatty alcohol mixture thus obtained contains about 25 to 30% of triacontanol. The residual soap after extraction of fatty alcohols is the source for long chain fatty acids (C22 and C24).
Level/Scale of Development 1-2 kg defatted wax / batch
Environmental Considerations The process does not generate any effluents.
Status of Commercialization Transferred the technology to four industries
Major Raw Materials to be Utilized Crude rice bran wax, alkali and organic solvent.
Major Plant Equipment and Machinery Required Autoclave, Soxhlet and Solvent Distillation System
Techno-Economics Technically and economically feasible as it is being produced by industry
Technology Package Available
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Annona Seed Extract as Insecticide
Title of Product/ Process/ Design/ Equipment Annona Seed Extract as Insecticide
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian & Foreign Patents Obtained
US 6991818 B2
Application/Uses Botanical Pestcide or Biopesticide
Salient Technical Features including Competing Features Solvent extraction procedures
Level/Scale of Development 5Kg batch process
Environmental Considerations Benign
Status of Commercialization Demonstrated earlier
Looking for Clients
Major Raw Materials to be Utilized Available in India
Major Plant Equipment and Machinery Required Feasible
Techno-Economics Feasible
Technology Package  
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Neem Seed Extract as Insecticide
Title of Product/ Process/ Design/ Equipment Neem Seed Extract as Insecticide
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian & Foreign Patents Obtained
US5856526
Application/Uses Botanical Pestcide or Biopesticide
Salient Technical Features including Competing Features Solvent extraction procedures.
1Kg seeds provides ~15 g extract
~30% Isosquamosin with others.
Level/Scale of Development 5Kg batch process
Environmental Considerations Benign
Status of Commercialization Demonstrated earlier
Looking for Clients
Major Raw Materials to be Utilized Available in India
Major Plant Equipment and Machinery Required Feasible
Techno-Economics Feasible
Technology Package  
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Nitriminoimidazole (NIIMD)
Title of Product/ Process/ Design/ Equipment NITRIMINOIMIDAZOLE (NIIMD)
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian Patent Obtained
DEL 1418
Application/Uses Intermediate required in making Imidacloprid pesticide
Salient Technical Features including Competing Features No Organic Solvent used
Level/Scale of Development 500g batch process
Environmental Considerations Benign
Status of Commercialization To be commercialized
Major Raw Materials to be Utilized Available in India
Major Plant Equipment and Machinery Required Feasible
Techno-Economics RMC cost = ~Rs.250/-
(US$7-8/Kg)
Technology Package  
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Bisphenol-Diazonaphthaquinone sulfonyl Esters - Photoactivating Compound
Title of Product/ Process/ Design/ Equipment Bisphenol-Diazonaphthaquinone sulfonyl Esters - Photoactivating Compound
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian and Foreign Patents Obtained:(i)US8563215 B2; (ii) EP 2137140 B1;m (iii) JP2010522230 A; (iv) WO 2008/117308 A4
Application/Uses In Making PCB; Electronic Industry
Salient Technical Features including Competing Features Strategic Chemical;
Mild Experimental Conditions; High Sensitivity
Level/Scale of Development 500 g Batch Process
Environmental Considerations Benign
Status of Commercialization Demonstrated to SSPL-DRDO Lab.
Looking for Suitable Client
Major Raw Materials to be Utilized Available in India
Major Plant Equipment and Machinery Required  
Techno-Economics Feasible
Technology Package  
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

sem1

...top


 
Diazonaphthaquinone sulfonylchloride
Title of Product/ Process/ Design/ Equipment Diazonaphthaquinone sulfonylchloride
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian and Foreign Patents Obtained
Application/Uses In Making PCB; Electronic Industry
Salient Technical Features including Competing Features Strategic Chemical;
Mild Experimental Conditions
Level/Scale of Development 500 g Batch Process
Environmental Considerations Benign
Status of Commercialization Demonstrated to SSPL-DRDO Lab
Looking for Suitable Client
Major Raw Materials to be Utilized Available in India
Major Plant Equipment and Machinery Required  
Techno-Economics Feasible
Technology Package  
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Pyriproxyfen
Title of Product/ Process/ Design/ Equipment Pyriproxyfen
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details To be filed
Application/Uses Juvenile hormone analogue (Insecticide)
Salient Technical Features including Competing Features Water mediated reaction steps; metal free conditions
Level/Scale of Development 10 Gram level
Environmental Considerations Benign
Status of Commercialization Looking for sponsorship
Major Raw Materials to be Utilized 4-chloronitrobenzene, Phenol etc..
Major Plant Equipment and Machinery Required  
Techno-Economics Economically viable
Technology Package Lab scale demonstration
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs)  

...top


 
Profenofos
Title of Product/ Process/ Design/ Equipment A mercaptan free process for Profenofos
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Yet to be filed
Application/Uses Profenofos an important member of the Organothiophosphate class of insecticides is a cholinesterase inhibitor, non-systemic insecticide and acaricide with contact and stomach poison. Profenofos is very effective on cotton pests especially white fly menace and controls Lepidoptera insects and Mites in cotton, tobacco, sugar beet, soya beans, vegetables etc.
Salient Technical Features including Competing Features With a view to overcome the pollution problem and to provide a better quality product, an innovative clean, green and cost effective technology was worked out avoiding mercaptan release. IICT approach for manufacture of profenofos involves 4 steps and cheap raw materials, which are also easily available, and therefore is easy to commercialize. The product is odourless and has a better impurity profile.
Level/Scale of Development Bench Scale -- 500 g/batch
Environmental Considerations IICT approach is a mercaptan free route, so overcomes a major effluent and pollution problem. It is an environmentally benign and cost effective technology.
Status of Commercialization The process has already been demonstrated to M/s IPL, Lucknow at half-a-kilogram level
Major Raw Materials to be Utilized 2-Chlorophenol, Bromine, inorganic and organic bases, n-Propyl bromide, DETC etc.
Major Plant Equipment and Machinery Required  
Techno-Economics Alternative to Monocrotofos and Endosulfan, which are being phased out in India. PROFENOFOS has Efficacy equivalent to Monocrotofos but has higher degree of safety to mammals.
Technology Package  
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) profeno
profeno

...top


 
Process Development of Misoprostol
Title of Product/ Process/ Design/ Equipment Process Development of Misoprostol
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Nil
Application/Uses Prostaglandin base drug used to prevent gastric ulcers, treat missed miscarriage, induce labor, and induce abortion.
Salient Technical Features including Competing Features Synthesis, Scale-up, Purification, Stabilization and Formulation.
Level/Scale of Development 100 g at CSIR-IICT
10 Kg at Industry
Environmental Considerations Greener approach (low catalyst loading, reduced reaction sequences, atom economy approach, reduction in solvent usage)
Status of Commercialization Commercialized 2013-14 (AVRA Laboratories Pvt. Ltd. Hyderabad, India)
Major Raw Materials to be Utilized Furan, diemthyl suberate and propargyl bromide
Major Plant Equipment and Machinery Required Chemical Reactors, Prep. HPLC and Flash chromatography
Techno-Economics 350 crore per year in Indian Market
Technology Package Starting from lab scale synthesis to scale-up and formulation.
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in

...top


 
1,1,1,2-Tetrafluoroethane (HFC-134a)
Title of Product/ Process/ Design/ Equipment 1,1,1,2-Tetrafluoroethane
(HFC-134a)
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details WO 0174483 (Oct 2001)
GB 2375974
CA 2403117
CN 1233459
AU 777841B
US 7982074 (July 2011)
Application/Uses Use in refrigeration & air conditioning
Salient Technical Features including Competing Features Well recommended substitute for chlorofluorocarbons (CFCs)
Level/Scale of Development Pilot scale
Environmental Considerations Ozone friendly
Status of Commercialization Under implementation by M/s. SRF, New Delhi
Major Raw Materials to be Utilized Trichloroethylene, AHF
Major Plant Equipment and Machinery Required Reactor system with specialized material of construction include, Monel, Inconel, Hastelloy
Techno-Economics Economically viable
Technology Package Available for exploitation
Contact Details Dr. B. Narsaiah, Chief Scientist & Head, Fluoroorganic Division
CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.
Ph. 27193185
Photographs (please provide high quality photographs) Lab scale & Pilot scale enclosed

...top


 
An improved process for the preparation of 2H-Heptafluoropropane
Title of Product/ Process/ Design/ Equipment An improved process for the preparation of 2H-Heptafluoropropane
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details 1830/DEL/2007
Published : 2009-04-03-CSIR
Application/Uses Product has fire extinguishing application in strategic and occupied areas and also used in aerosols for medical application
Salient Technical Features including Competing Features Continuous catalytic vapor phase fluorination process resulting in excellent selectivity and yield.
Level/Scale of Development 70 g/h
Environmental Considerations Ozone friendly product and an excellent replacement for halons
Status of Commercialization Transferred to M/s. GFL, Gujarat for commercial production
Major Raw Materials to be Utilized AHF and Hexafluoropropylene
Major Plant Equipment and Machinery Required Inconel tubular reactors with external heat exchangers
Techno-Economics Economically viable process and the product is an import substitute
Technology Package  
Contact Details Dr. B. Narsaiah, Chief Scientist & Head, Fluoroorganic Division
CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.
Ph. 27193185
Photographs (please provide high quality photographs) Enclosed

...top


 
1,1,1-trifluoro trichloroethane (CFC-113a)
Title of Product/ Process/ Design/ Equipment 1,1,1-trifluoro trichloroethane (CFC-113a)
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian IN194697 (2006)

Application/Uses Raw material for ƛ-cyhalothrin, a pyrethroid
Salient Technical Features including Competing Features Lewis acid catalyzed isomerisation of CFC-113.
Level/Scale of Development 5 kg / batch
Environmental Considerations Starting material CFC-113 is banned and the process developed to a value added product
Status of Commercialization Scaleup studies are required
Major Raw Materials to be Utilized CFC-113 and Lewis acids
Major Plant Equipment and Machinery Required A jacketed glass lined reactor with cooling facility
Techno-Economics Technically feasible
Technology Package Lab scale process
Contact Details Dr. B. Narsaiah, Chief Scientist & Head, Fluoroorganic Division
CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.
Ph. 27193185
Photographs (please provide high quality photographs) ----

...top


 
Trifluoro acetic acid
Title of Product/ Process/ Design/ Equipment Trifluoro acetic acid
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Not patented

Application/Uses Fine chemical
Salient Technical Features including Competing Features Hydrolysis of CFC-113a
Level/Scale of Development Semi continuous process
Environmental Considerations --
Status of Commercialization Commercially produced based on our process
Major Raw Materials to be Utilized CFC-113a
Major Plant Equipment and Machinery Required Tubular reactor
Techno-Economics Technically feasible. Economics were worked out by sponsor
Technology Package Lab scale process
Contact Details Dr. B. Narsaiah, Chief Scientist & Head, Fluoroorganic Division
CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.
Ph. 27193185
Photographs (please provide high quality photographs) ---

...top


 
2,2,2-Trifluoro ethanol
Title of Product/ Process/ Design/ Equipment 2,2,2-Trifluoro ethanol
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian IN 247629 (2011)
Application/Uses Fine chemical
Salient Technical Features including Competing Features High atom economy process
Level/Scale of Development 200 g batch process
Environmental Considerations Eco-friendly process
Status of Commercialization Lab scale process available
Major Raw Materials to be Utilized HCFC-133a and metal acetate
Major Plant Equipment and Machinery Required Autoclave
Techno-Economics Technically feasible
Technology Package Scaleup studies required
Contact Details Dr. B. Narsaiah, Chief Scientist & Head, Fluoroorganic Division
CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.
Ph. 27193185
Photographs (please provide high quality photographs) ---

...top


 
Samadhan Kendra
Title of Product/ Process/ Design/ Equipment Samadhan Kendra: A Rural Information Technology Centre for Rural Development in India
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details (*Copyright with CSIR). entitled "SAMADHAN KENDRA an Information Technology Centre for Rural Development"
Year: 2009
Country:  India.
Application/Uses   The SAMADHAN KENDRA is Rural Information Technology centre for the benefit of community in rural areas. It is integrated web based, user-friendly software. It aids in dissemination of information through audio-visual effects which help the rural population. It has Graphical User Interface (GUI) with icons and diagrams which are easily identifiable and navigable by rural people. This has several built-in features for rural population like agriculture practices of that particular study area i.e. pest disease information system (PDIS) on the major crops, control measures to be adapted, seed information, nutritional status of soil, soil type required for various crops, details about horticultural crops etc., This also gives the information on seed management, quality, availability, fertilizer details like procurement, application dosages, schedule etc provided by the Samadhan Kendra. The software also provide the details about Govt. schemes, subsidies and loan facility, list of banks which offer loans on agriculture, health, education etc. for the benefit of the rural population. Farmers can down load the relevant application forms from the Samadhan Kendra. Public Health details like hospitals, primary health canters, availability of medicines and vaccines were given to facilitate the local rural population.

  Early detection of pests and diseases is a critical component for agricultural sustainability. The Samadhan centre helps the farmers in the aspects of crop management, soil tillage, adoption of seeds, fertiliser usage, and other allied components of agricultural practice. In a nutshell this novel technology helps to change the nature of crop management practices in the backward districts of Andhra Pradesh. It helps in sustained productivity, maintaining quality thereby increasing the income of farmers. It is estimated that each centre was able to provide a net gain of 20-30% in crop productivity increase and thereby providing additional income.

  Success of any technology depends on the interest of end users. More than 75% population of this country belongs to rural areas. Therefore the IT application for the rural development has bright future in the coming Information era in the country like India. Samadhan Kendra is a Sustainable Rural Information Centre, which would be able to provide various IT, related services to the rural public and to concerned government departments.
Salient Technical Features including Competing Features
  • Cost effective and User-friendly software easy to navigable
  • Audio and video output
  • Easily accessible as it will be situated in a nearby village Downloadable application forms required by the farmers through single window system.
  • Immediate response for trouble shooting problems like pest control, availability of fertilizers, cots of the material, suitability of the crops according to the type of soil etc…
  • One Samadhan Kendra can serve the purpose of 20 villages approximately so that 1,00,000 population.
Level/Scale of Development This software has been developed and it can be modified based on local requirements both on audio and visual
Environmental Considerations -N/A-
Status of Commercialization Each Samadhan Kendra is established in a centrally located village that is easily accessible by the populace of the other villages. Such types of Kendra have been established in various parts of Andhra Pradesh, Telangana and Uttar Pradesh.
  1. Ganesh Rural Development Society, Prattipadu, Gudem Mandal
  2. Dedication for Education Economic Development Society, Nallajerla, Gudem Mandal
  3. Geetha Sai Rural Development Association, Pydiparru Tanuku, Mandal
  4. Grameena Mahila Vikas Society, Balusumudi, Bhimavaram.
  5. Farmers Federation of Associations, Hyderabad.
  6. Ashok Samsatan, Uttar Pradesh.
  7. Under CSIR TechVill program, all the Techvill will be equipped with one Samadhan Kendra based on the local requirements.
Major Raw Materials to be Utilized -N/A-
Major Plant Equipment and Machinery Required An amount of Rs. 4 to 5 lakh will be required to establish each Samadhan Centre, (computers, printers, scanners and other miscellaneous expenditure) and dedicated building.
Techno-Economics It helps in sustained productivity, maintaining quality thereby increasing the income of farmers. It is estimated that each centre was able to provide a net gain of 20-30% in crop productivity increase and thereby providing additional income. The Gummadidala Samadhan centre, Medak district, where the facilities were established has a population of 6000. In addition to this village Solakpalli,Puttaguda, Pyaranagar, Nulthur, Pallem, Mangapalli, Nallapalli, Madhapur and other villages in the area of 25-30 kilometres with a population of 80,000 to 90,000 are benefited by this centre. During the year 2010-11 it is estimated that about 70,000 mango farmers were benefited in Chittoor District (Samadhan Centre established by FFA) alone due to the effective role played by "Samadhan Kendra" in disseminating the day to day minimum price for the mango crop without the intervention of the middle men or the commission agents.
Technology Package It is integrated web based, user-friendly software. The software is built using the JAVA web applet and web pages are developed using html. The Samadhan Kendra has Graphical User Interface (GUI) with icons and diagrams representing the all the topics which are easily identifiable and navigable by rural people. This has several built-in features for rural population like agriculture practices of that particular study area i.e. pest disease information system (PDIS) on the major crops, control measures to be adapted, seed information, nutritional status of soil, soil type required for various crops, details about horticultural crops etc.,
Contact Details Director, CSIR-Indian Institute of Chemical Technology,
Dr, USN Murty, Chief Scientist, Head, Biology Division
Tarnaka, Hyderabad - 500007, India.

Phone: 91-40-27193030;
Fax: 91-40-27160387
E-mail: director@iict.res.in
Photographs (please provide high quality photographs) samadha

...top


 
Pyridone derivatives
Title of Product/ Process/ Design/ Equipment Pyridone Derivatives
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Indian Patent Under preparation
Application/Uses Used as Cardiotonic Agents for Heart Diseases as Specific PDE3a Inhibitor
Salient Technical Features including Competing Features Simple procedure
Level/Scale of Development 5 g Batch Process
Environmental Considerations  
Status of Commercialization Looking for Suitable Client
Major Raw Materials to be Utilized Available in India
Major Plant Equipment and Machinery Required  
Techno-Economics Feasible
Technology Package  
Contact Details Head BMA, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.
Photographs (please provide high quality photographs)  
pde
PDE5 inhibitory activity of Indolizidine derivatives (500 µM in DMSO).Standard Drug: Sildenafil (500 µM in DMSO).

...top


 
Avobenzone
Title of Product/ Process/ Design/ Equipment AVOBENZONE
IPR Status Patent/ Copyright/ Trademark Secured in India/ Abroad IPR Details Off-Patent
Application/Uses Sunscreen product; Used in Skin-lotions
Salient Technical Features including Competing Features Strong absorption of Ultraviolet A (320-400 nm, associated with long term skin damage) and Ultraviolet B (290-320 nm, causes sunburns). This light range is better than most other organic sunscreen technologies and marked as broad spectrum sunscreens
Level/Scale of Development 100 grams
Environmental Considerations Benign
Status of Commercialization Process Demonstrated
Major Raw Materials to be Utilized 4-Methoxyacetophenone, methyl 4-tert-butylbenzoate, NaNH2, Toluene
Major Plant Equipment and Machinery Required  
Techno-Economics Feasible
Technology Package  
Contact Details Head BMA, CSIR-Indian Institute of Chemical Technology,
Tarnaka, Hyderabad - 500007, India.
Photographs (please provide high quality photographs)  

...top


CSIR |  Events |  Contact Us |  Feedback | fbfmi | twfmi | ytfmi
Copyright: CSIR-IICT 2015
Visitiors  152162