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Mass & Analytical (NCMS)

Overview

Mass spectrometry is a powerful and versatile analytical technique for the analysis of organic and biomolecules, mainly for determination of their molecular weight and structural characterization. Because of its high sensitivity, selectivity and speed, mass spectrometry finds application in several diverse fields, such as, chemistry, physics medicinal chemistry, biochemistry, pharmaceutical science, biological sciences, geology, cosmo-chemistry, nuclear science, material science, archaeology, petroleum industry, forensic science, and environmental science. Mass spectrometry has become an integral part of proteomics, metabolomics, lipidomics and the drug development process. Mass spectral analysis of products and various intermediates generated during process development helps in process control very effectively.

The Mass Spectrometry Centre at CSIR-IICT has been recognized as the National Centre for Mass Spectrometry (NCMS) by the Department of Science and Technology (DST), Government of India in 1999. The Center is well equipped with the state-of-art, equipments which includes GC-MS, LC-MS/MS, Q-TOF, Ion Trap, GC-TOF, MALDI-TOF/TOF and Orbitrap mass spectrometers to facilitate characterization of various types of analytes ranging from small organic molecules to large molecules such as polymers and biomolecules. The Centre provide knowledge based ISO 9001: 2008 certified services to all IICT projects, industry, academic institutes, governmental agencies etc. We have been working on two major 12th five year plan net work projects (Metabolomics and Augmentation of Analytical facilities). In addition, we also deal with several consultancy projects from chemical industries, academia and other governmental and non-governmental agencies and contribute to the ECF of IICT. The Center also imparts advanced training to post graduate and doctoral students. NCMS has been engaged in basic and applied research in mass spectrometry and published more than 400 research papers in reputed international journals. 35 students were awarded Ph.d Degrees and about 20 students are pursuing Ph.ds. In addition, several PG students here done their project dissertations.

The Centre for Analysis of Chemical Toxins, a part of NCMS, is an OPCW (Organization for Prohibition of Chemical Weapons, The Netherlands) designated laboratory for off-site analysis of chemicals related to chemical weapons convention (CWC). To maintain the designated status, which is strategically important to our country, IICT has been successfully participating in the international official OPCW proficiency tests every year. Recently, the OPCW received Nobel Peace Prize (2013) for its extensive efforts to eliminate chemical weapons from the world. On this occasion, the Director General of the OPCW had shared his joy and specially thanked CSIR-IICT for its significant contributions as its partner laboratory towards achieving the common goal for a world free of chemical weapons.

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